Cardiology Facts 19

 

  • Insulin-like growth factor-1β is inhibitors of cardiac myocyte apoptosis
  • Beta blockers offer less protection against stroke than other antihypertensive agents
  • Smoker, pain & discoloration of fingers of hand - Buerger's disease, abstain from smoking
  • Peak age range for surgical intervention for patients with bicuspid aortic valve is 60 to 80 years
  • Diabetes mellitus target BP stage 2, 130/80 mmHg 
  • Evidenced-based extended-duration regimen to reduce risk of recurrent VTE is with warfarin INR target 2.0 to 3.0 or warfarin INR target 1.5-2.0, aspirin 100 mg daily, apixaban 2.5mg BD 5mg BD, rivaroxaban 20 mg 10 mg OD 
  • Obesity, HTN, falling asleep while driving - diagnosis obstructive sleep apnea, test polysomnography
  • Severe three vessel CAD without left main stenosis, <65 years age, non smoker, no history of stroke/TIA, or carotid bruit, peripheral pulses are 2+. No further testing required prior to CABG 
  • Multiple risk factors for CAD, dyslipidemia, taking rosuvastatin 20 mg/day, additional therapies recommended include nicotinic acid, fenofibrate, ezetimibe, intensification of diet, exercise, weight loss program, increase rosuvastatin to 40 mg/day 
  • BAV mean gradient 42 mm Hg, chest irradiation - TAVI