Cardiology Facts 27

 

  • Myxomatous mitral valve disease no antibiotic prophylaxis prior to dental procedures 
  • Prophylaxis before dental extraction in patient with bioprosthetic aortic valve is amoxicillin, 2g orally, taken 30 to 60 minutes
  • 50% with popliteal artery aneurysm have concomitant AAA 
  • 5 Ps of acute limb ischemia are: pain, paralysis, paresthesia, pallor, pulse deficit and poikilothermia 
  • STEMI, nearest hospital with PCI facility located more than 120 minutes away - management IV tenecteplase, aspirin, clopidogrel, unfractionated heparin. Even after complete resolution of chest pain & ST elevation continue unfractionated heparin, aspirin, clopidogrel and transfer to nearest hospital with PCI capabilities 
  • There is shared genetic predisposition to some PPCM cases and other forms of dilated cardiomyopathy 
  • Pindolol has intrinsic sympathomimetic activity, propranolol has membrane-stabilising activity, labetalol has α-blockade activity, bisoprolol has β1-selectivity (bi=beta-1) 
  • Trastuzumab causes loss of myocardial contractility HFrEF 
  • Tenecteplase prolonged half-life allows administration as single bolus 
  • Plaque rupture is dominant initiating event in pathogenesis of ACS