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- Nitric oxide causes increased smooth muscle proliferation in endothelium
- Hypertension is most responsible risk factor for increased burden of HFpEF
- Medtronic Hall valve is single tilting disc valve
- Prevent transplant vasculopathy - statins, HTN & DM control, avoidance of smoking
- Prominent S2, holosystolic murmur at right lower sternal border, RV heave - right heart catheterization for pulmonary pressures and determining whether pulmonary hypertension is due to pulmonary vasculopathy (with normal PCWP) or pulmonary hypertension due to left heart disease (elevated PCWP)
- Class II drugs block beta-adrenergic receptors
- No antibiotic prophylaxis is recommended prior to dental procedures for people with mitral valve prolapse
- During second trimester of pregnancy there is increase in CO and decrease in SVR
- CRT improves myocardial performance without increasing myocardial oxygen consumption
- NSTEMI, high risk criteria (increasing frequency of chest pain, elevated troponin, echocardiographic abnormalities) - early invasive strategy, coronary angiography within 48 hours followed by PCI/surgery