Cardiology Facts 33

 

  • Osler nodes are small, raised red (or purple) tender lesions present in pulp spaces of terminal phalanges of fingers
  • Flushing, wheeze, diarrhoea, elevated JVP, TR, pulsatile liver, peripheral edema, high urinary 5-hydroxyindoleacetic acid - carcinoid syndrome, involves liver 
  • Recommended range to achieve optimal efficacy and safety if anticoagulation for VTE with DTI is aPTT 1.5 to 2.5 times baseline 
  • In-hospital cardiac arrest is associated with significantly higher survival rate than out-of-hospital cardiac arrest 
  • Class IV drugs block slow calcium channels 
  • JUPITER trial : primary prevention patients with only modest elevations in LDL-C but elevated usCRP above 2 mg/L benefited from statins. There was no comparison to individuals with low LDL-C and low usCRP 
  • Procainamide, loading dose = Vd × Cpss 
  • Heart failure, ferritin 100-299 ng/mL, iron saturation <20% - IV iron sucrose 
  • Bivalirudin binds directly to thrombin, independent of antithrombin 
  • Mortality benefit with routine intravenous nitroglycerin is not established in primary PCI