Cardiology Facts 48


  • Pulmonary embolism, hypotension - give alteplase 100 mg IV over 2 hours
  • Heparin does not inactivate clot-bound thrombin 
  • Type A aortic dissection, dissection flap involving sinuses of Valsalva on chest CT aortography is associated with highest mortality 
  • Cyanosis, digital clubbing, loud P2, Graham Steell murmur - Eisenmenger syndrome
  • Calcium channel blockers & epoprostenol (prostacyclin) have survival benefit in idiopathic (group 1) PAH
  • History of HTN, ischemic stroke, on aspirin, PCI DES - next start clopidogrel
  • ARBs reduce progression of aortic disease in Marfan syndrome by reducing activity of TGF-β 
  • Children with ASDs are underdeveloped physically and prone to respiratory tract infections 
  • PCI, sudden dyspnea, coarse breath sounds in lungs, high RV, PA, PCWP, low cardiac output - cause papillary muscle rupture
  • CABG using saphenous vein, leg wound not healing+ulcer+edema, USG venous valve incompetence in deep veins, to improve wound healing advise compression stockings