Cardiology Facts 18


  • Preeclampsia is hypertension after 20 weeks of gestation with >300 mg protein in 24-hour urine collection or >30 mg/mmol in spot urine sample. Eclampsia is occurrence of seizures in preeclampsia
  • Unfractionated heparin can cause increases vascular permeability
  • Early systolic click that does not change with inspiration, systolic murmur and diastolic murmur along left sternal border - bicuspid aortic valve with regurgitation
  • Long term antihypertensive mechanism of action for thiazide diuretics is decreased peripheral resistance 
  • Addition of fibrates and niacin to higher dose statins to achieve non HDL-C goals has not shown to achieve secondary targets and further reduce cardiovascular event rate
  • Acute ischemic stroke does not receive thrombolytics, BP <220/120 mm Hg, in first 24 hours of hospitalization antihypertensive therapy is not indicated
  • Pulmonary arterial hypertension is complication of systemic sclerosis 
  • Libman Sacks endocarditis is complication of SLE 
  • Weber-Osler-Rendu syndrome is associated with pulmonary arteriovenous fistula
  • Statins have not been shown to worsen outcome with chronic transaminase elevations due to hepatitis B or C